Estudio clínico de 113 casos de melanoma maligno / Clinical study of 113 cases of malignant nelanoma

Malignant melanoma (MM) incidence rate is increasing faster than many other cancer at present time. Its epidemiological and clinical behavoir varies within countries. We have studied 113 cases of cutaneous melanoma from 1982-1993, that represents until now the largest series of MM studied in Chile. Superficial Spreading Melanoma was the most common type of MM with 37.5 percent of total cases followed by Nodular Melanoma 31.2 percent, Acral Melanoma 22.1 percent and Lentigo Malignant Melanoma with 7.8 percent. MM favored females with 60.2 percent (n=68) and males constituted 39.8 percent (n=45) of all cases. Median age at diagnosis was 54 years. Primary more frequent location for man was thorax (36.4 percent) and lower extremities for women (28.6 percent). Hemorrhage, ulceration and rapid growth of a previously pigmented lesion as the primary cause for first medical visit were associated with high level of invasion, generally over 2 mm. thick. Color change and pruritus were associated with lower level of invasion. Patients in stage I (78.3 percent) had 1.35 mm of median invasive thickness in the primary lesion and patients in stage II (15.7 percent) had 3.03 mm

Tricofoliculoma: a propósito de un caso / Trichofolliculoma: apropos of 1 case

Los tumores anexiales generalmente se clasifican de acuerdo a la estructura de la cual presumiblemente derivan. El Tricofoliculoma se ubica entre los tumores bien diferenciados de la unidad pilosebácea. Clínicamente se presenta como un nódulo cupuliforme, único, de color piel, con un pequeño orofocio central desde el cual puede protruir un mechón de pelos blancos algodonosos. Está confinado a la cabeza y cuello más comunmente que en la cara. Histológicamente se presenta como un folículo primario o una cavidad central, dilatada, de contenido queratínico variable y tapizada por un epitelio escamoso pluriestratificado, conectado a la epidermis vecina, desde la cual emergen brotes epiteliales secundarios que protruyen hacia la dermis, en forma radiada, conformando folículos secundarios, los cuales en ocasiones presentan pelo en su interior. Presentamos el caso de un paciente de sexo femenino portadora de este tumor y hacemos una breve revisión y planteamiento de sus diagnósticos diferenciales, tanto clínicos como histopatológicos